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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGALS3
All Species:
26.97
Human Site:
Y221
Identified Species:
59.33
UniProt:
P17931
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17931
NP_002297.2
250
26152
Y221
N
D
A
H
L
L
Q
Y
N
H
R
V
K
K
L
Chimpanzee
Pan troglodytes
XP_001148424
357
37768
Y328
N
D
A
H
L
L
Q
Y
N
H
R
V
K
K
L
Rhesus Macaque
Macaca mulatta
XP_001085890
255
27015
Y226
N
D
A
H
L
L
Q
Y
N
H
R
V
K
Q
L
Dog
Lupus familis
XP_853675
287
29487
Y258
N
D
A
H
L
L
Q
Y
N
H
R
M
K
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P16110
264
27496
Y235
N
D
A
H
L
L
Q
Y
N
H
R
M
K
N
L
Rat
Rattus norvegicus
P08699
262
27183
Y233
N
D
V
H
L
L
Q
Y
N
H
R
M
K
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507412
266
27642
Y237
N
D
A
H
L
L
Q
Y
N
H
R
M
R
D
L
Chicken
Gallus gallus
Q5ZHQ2
171
19026
L143
I
F
V
D
G
H
Q
L
F
D
F
Y
H
R
I
Frog
Xenopus laevis
Q6DDR8
171
19215
L143
I
F
V
D
G
H
Q
L
F
D
F
Y
H
R
V
Zebra Danio
Brachydanio rerio
Q6DGJ1
139
16307
V111
V
M
Q
Y
K
H
R
V
E
D
L
K
T
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P36573
279
31791
Y250
V
F
V
N
G
E
R
Y
I
S
F
A
H
R
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.6
91.7
76.6
N.A.
80.3
80.5
N.A.
68.8
21.2
24.7
23.6
N.A.
N.A.
N.A.
24.7
N.A.
Protein Similarity:
100
68.9
93.3
81.1
N.A.
86.3
86.2
N.A.
75.5
35.2
37.5
35.5
N.A.
N.A.
N.A.
40.1
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
80
N.A.
80
6.6
6.6
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
93.3
20
20
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
55
0
0
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
64
0
19
0
0
0
0
0
28
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
28
0
0
0
0
0
0
19
0
28
0
0
0
0
% F
% Gly:
0
0
0
0
28
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
64
0
28
0
0
0
64
0
0
28
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
10
55
19
0
% K
% Leu:
0
0
0
0
64
64
0
19
0
0
10
0
0
0
64
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
37
0
0
0
% M
% Asn:
64
0
0
10
0
0
0
0
64
0
0
0
0
28
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
82
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
19
0
0
0
64
0
10
28
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% T
% Val:
19
0
37
0
0
0
0
10
0
0
0
28
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
73
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _